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Kristen Bell and Dax Shepard go head-to-head in the Battle of the Sexes, a series of games designed to find out how men’s and women’s brains differ.
Actor Ted Danson and special guests Blue Man Group play along with host Keegan-Michael Key as we learn how our brains distinguish fact from fiction.
New Orleans Saints NFL quarterback Drew Brees puts his brain to the test with a series of mental challenges exploring how we can train our own minds to do as we want.
Actor Anthony Anderson and his co-star Marsai Martin face off in a series of games with Keegan-Michael Key.
Actor-musician Jack Black and his Tenacious D bandmate Kyle Gass learn how music affects the brain.
Keegan-Michael Key welcomes billionaire CEO and reality star Mark Cuban ("Shark Tank") to the show.
Actress Rebel Wilson joins Keegan-Michael Key to explore the power of the subconscious when it comes to falling in love.
Actress Tiffany Haddish and director Jordan Peele join Keegan-Michael Key to play a series of games.
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