Sandra and Mart were childhood friends who only saw each other every summer. Time passed by and their friendship turned into romance despite their young age. Even after Sandra moved to Bulacan with her grandmother, the two remained in contact and in love. Things started to fade when Mart began neglecting his boyfriend duties to Sandra and even ignored her efforts to save their relationship. With high hopes for the future, Sandra decided to break up with him and left him a letter professing her love and her willingness to wait for him. Did they have a second chance at love? Did Mart realize that he still loved Sandra?

Since his high school days, Tim is a carefree bachelor who only thinks of himself, while Jung Won is a Korean student and social worker assigned in an international NGO in the Philippines. Tim's perspective in life changes when he meets Jung Won and falls in love with her. Even if Jung Won focuses on her studies and in helping poor communities, Tim remains persistent just to get her heart. His efforts eventually pays off when Jun Wong finally reciprocates his love. Their relationship is going smoothly until Jung Won decides to finish her studies in South Korea. Will this challenge mark the end of Jung Won and Tim's love story?

John meets Aika just as when she is recovering from a broken heart. He pursues her, but Aika is reluctant to start a relationship with him for fear of getting hurt again. She suppresses her feelings, until she can no longer deny that she has completely fallen for John. She gives their love a chance and her fear of being left behind disappears. The two are very happy together but not for long, because Aika gets diagnosed with leukemia. How will John and Aika deal with her illness? Will they continue what they have started? Who will fight until the end and who will give up?

Growing up in a poor family, Vin-zl strived hard to excel in her studies in order to give them a better life especially after her sister got pregnant. She promised herself that she would not end up the same fate as her sister's. However, her boyfriend Red unexpectedly got her pregnant that made her stop her studies. Nevertheless, her willingness to finish her studies didn't waver. Hence, after giving birth, her father and her husband supported her in continuing her studies. As she returns to school, how will she be able to balance being a student and being a mother to her daughter Vianca especially that she also needs to bring Vianca along with her to school?

Behind her happy disposition in life, Maymay grew up in an unideal family set-up. Her father left them when she was still very young while her mother decided to work in Japan to provide for her needs. She was practically raised by her grandparents who were the ones who filled the void in her heart. Maymay's world crumbled, however, when her beloved grandfather got hospitalized for his heart condition. This ordeal depleted the family's finances that even led to them selling their house just to sustain their everyday life. How did Maymay and her family coped in this very tough time? What prompted Maymay to join "PBB"?

Ever since Maya went to jail in 2008 for drug charges, her daughter Joy has been a constant visitor in the jail facility where she's detained. This is how they get to spend time and bond with each other. Joy's regular visits, however, also pave the way for her to meet Rustom, a young inmate who captivates her heart and causes tension between her and her mother. Maya's anger grows when she learns that Joy chooses to be with Rustom when he transfers to Manila. Will the relationship of Maya and Joy be fixed? How will Maya help her daughter cope once she learns about her husband's infidelity after she gives birth?

The first part tells the story from the vantage point of Idai, a mother whose child disappeared and was allegedly abducted by an unknown woman. Ever since her parents separated, Idai wanted nothing but to have a happy and complete family. Despite the hardships in life, she and her husband Alfredo strived hard to give their children what they needed and showered them with overflowing love and affection. One day, however, Idai's youngest child Topher went missing and was believed to have been abducted. Idai tried desperately to look for her son but to no avail. Little did they know that Topher was with a woman named Roma, who took the child with her to her hometown in Lanao. How did Idai reunite with her son Topher? Why did Roma take the child? What's her version of the story?

Samira finds a lost child and takes him as her own son. After a year, she gets in touch with Brombrom’s mother upon learning that his family is looking for him. To Samira's surprise, she and her sister get arrested for allegedly kidnapping Brombrom.

Behind the famous designs of Rocky is a kid who longs for a complete family. A week after he was born, his mother left him with his alcoholic and womanizer father. As time passed, Rocky realized that he was gay and was more in touch with his feminine side. Because of this, he decided to leave his father behind to look for his mother. However, their reunion wasn't exactly how he pictured it to be. His mother, unfortunately, chose her new family over him and didn't even welcome him with open arms. Rocky was then left wandering the streets of Roxas Boulevard all by himself. How did he survive this ordeal? What paved the way for Rocky to enter the world of fashion and become one of the Philippines' pride today?

Melanie's dream of supporting her mother turns into a nightmare when her co-worker rapes her. Despite her struggles, Melanie learns to love and accept her daughter, Mae Ann, until her child learns of her dark past.

Hershey takes matters into her own hands as her abusive mother neglects her siblings. When she is forced to marry a rich Korean man, she runs away to find a new life and support her family.

Charice Pempengco, (later known as Jake Zyrus) wanted nothing but for people, especially his mother, to accept him for who he is. He was a young kid then when he first observed that he was more attracted to women than men. As he grew up, he also grew certain about his gender, yet he still chose to act and dress as a woman in public so as not to jeopardize his career. How did Jake manage to hide his true identity all these years? What pushed him to finally be true to himself and re-introduce himself as Jake Zyrus?

Ever since she adopted the little boy from her niece, Guily has always treated Jayson as her own. It did not take long for Jayson to find out the truth about his identity after he noticed he was using a surname different from his parents'. After knowing that his biological mother was still alive, Jayson grew up longing to meet her. Being a child out of wedlock, Guily fully understood what he was going through, so one day, she accompanied him to his mother Chona. Jayson's much awaited moment, however, did not happen how he pictured it to be. What happened when Jayson finally came face-to-face with Chona? How did the encounter affect his life?

To find herself again after a break-up, Mae decided to join a hiking team. On her first hike, she met Pio, one of the organizers and later on the man who will mend her broken heart. The two became an official couple and their relationship was going strong until Mae got pregnant. Mae was afraid at first, but Pio stayed by her side and even asked her hand in marriage. Everything seemed perfect until one day, Pio got rushed to the hospital and was diagnosed with viral encephalitis, a rare brain disease that affects the memory of the person. How will Mae surpass this ordeal? What will she do as Pio's memory starts to deteriorate? What future awaits her and her unborn child?

Ever since he was born, George has been dependent on his family especially on his brother Baning and sister Bernadeth. Together, they dream of finishing school together. Everything was going smoothly until Bernadette found a new set of friends and started to feel embarrassed that she has to carry her older brother to school. Despite this, Baning never left George's side and continued to serve as his legs so he can go to different places. But how far can Baning really go for his brother? Will he go as far as giving up his own dreams? As the two enter college, they are confronted with the dilemma that they want to take two different courses- George wants to pursue Business Administration, while Baning wants to take criminology.

Hazel was still a teenager when she left her family to go with her aunt who offered to finance her studies. She was then full of hopes and dreams, until her aunt's husband shattered them all when he took advantage of her. Devastated by what happened, Hazel came home to the province. Fate, however, remained unkind to her when another man, Bensyo, sexually abused her. Bensyo did not only sell her to a prostitute house but also got her pregnant. How did Hazel face this ordeal? How did she escape the terrible and dark world she lived in?

Cenia and husband Dodong were living happily with their seven children, until rumors of Dodong having an affair with another woman circulated in the neighborhood. Truth about Dodong's infidelity, however, was confirmed not by Cenia but by their eldest daughter Waway. Both Cenia and Waway were then filled with anger and despair. But the hurt did not end there because Dodong got Ani pregnant and even asked Cenia to take care of Ani and his illegitimate child in his dying seconds. Fulfilling Dodong's death wish, Ani and her child stayed in Cenia's home. How long can Cenia keep up with the situation? Did Cenia and Ani get along?

Way before he made dresses for Anne Curtis, Kim Chiu, Kris Aquino and Miss Universe 2015 Pia Wurtzbach, Rey already knew that he was gay like his brother Brian. However, when he saw how Brian suffered after opening up about his sexual orientation, he chose to hide his real identity. Growing up, Rey looked up to Brian because of the courage and hard work his brother invested in the fashion line business the latter owned to prove their father wrong, which Rey thought he could not do. Although unexpected, their father eventually accepted Brian's identity, but Rey still continued his pretense and even pursued a career as a flight attendant. Until one day, Brian got involved in a holdup incident that caused his death and would change Rey's life forever.

Josephine sets aside her own life in order to take care of her mother Carmen, who is suffering from Alzheimer's disease.