Kicking off the race from a brand new location, 10 teams start off in Bangkok, the capital of Thailand, gunning for the top prize of US$100,000. The first Detour of the race was a choice between Race or Rice. In Race, teams had to proceed to the Chiang Mai X-Centre and drive an off-road buggy over an 8 km track to receive their next clue. In Rice, teams must work together to pound rice into paste and make two rice balls using a traditional method, subjected to approval.

After an arduous first leg that saw teams indulge in some bugs and insects, wash a two storey bus and pound some rice, the remaining 9 teams are kicking off their second day. In the first Roadblock of this season, one team member had to cross the plantation and retrieve a clue from a hanging backpack. The catch was that along the way, snipers brandishing paintball guns would fire at the team member; once shot, the team member must return to the starting point and perform the task again until successful. In this leg's Detour, the choice was between Sampan and Some Walk. In Sampan, teams must transport fruits on a sampan and row across the river to a designated fruit stall along the river. In Some Walk, teams must gather twenty live chickens and bring them to a designated retailer in the nearby market.

From the Museum of Vietnamese History in Ho Chi Minh, 8 teams remain in the race towards US$100.000. Siblings Bernie and Henry take the lead in this leg, and teams must now travel by bus, to the city of Hue in central Vietnam. The catch is, Hue is over 1,000kn away and the bus journey takes slightly over 25 hours.

In this leg's Detour, teams had to choose between Shoot It or Shape It. In Shoot It, teams drive themselves to the Miniatures Museum of Taiwan and are told to use a Sony Cybershot camera to shoot a very miniature model of a yellow-race envelope hidden inside one of the dioramas. After the photo was printed, the next clue could be found behind their new photo. In Shape It, teams drive themselves to Raohe Street Night Market where they will have to solve four sets of figures using a large tangram set. In this leg's Roadblock, one team member had to completely consume an entire bowl of a Taiwanese/Chinese delicacy: stinky tofu.

As it stands, two teams have decided to bail out of the race by taking the four hour penalty for not completing a challenge. Can the other teams muster enough strength to continue with the race, or will more choose to take the easy way out? After the task at the Sony Style Store, teams received a Fast Forward option. The Fast Forward was to travel to a certain street, where there will find a clue box. The clue would then instruct them to get a permanent tattoo at Kevin's Tattoo. The Roadblock was to find a souvenir, which would later be revealed to be a small silver token that had the AXN logo on one side and The Amazing Race Asia logo on the other side in a cart of coal. In this leg's Detour the choice was between Pick or Pail. In Pick, teams had to drive themselves to a local mall and retrieve three soft toys from a game machine. In Pail, teams had to go to the Grand Tong Temple and must fill a bucket full of water and carry it to the top of the mountain where a monk will check to see if they had enough water. If they have enough they will receive their next clue.

It is the halfway point in the race, and only half of the original 10 teams remain to claim the prize of US$100,000. In this Detour, teams had to choose between Get Fishy or Get Lucky. In Get Fishy, teams had to find a seafood store in Graham Street to scale and gut 12 fishes to the satisfaction of a fishmonger, before they would receive their next clue. In Get Lucky, teams had to head to one of the designated tables at Mee Lun St. and bite into hundreds of fortune cookies in a marked jar and only when they find the one cookie which contains a fortune regarding their next clue can they proceed. In this Roadblock, one team member had to choose one of the provided handbags and search through the crowded market for the lady who is carrying the same handbag as the one the team member has chosen. This lady will hand them their final clue for the leg.

From one of the world's leading financial capitals, team Hong Kong, buddies Sam and Vince have a lot to celebrate. Not only are they home, but they have also emerged top in the previous leg of the race. In this leg's Roadblock, the chosen team member must climb to the top of the Macau Tower, obtain their next clue there, and go down back to their partner before reading their next clue. However, due to the storm, not all the teams who were still performing the Roadblock at the time were allowed to climb to the top as a precaution. In this leg's Detour, the choice was between Dance or Chance. In Dance, the team members must correctly perform a lion dance routine to the satisfaction of the performance troupe. In Chance, teams must don formal attire and play a game of blackjack in the casino of Hotel Royal Macau; they must beat the dealer nine times (as denoted by the letters of the word COMPLETED) before receiving their next clue.

Luck seems to be smiling on Malaysian mothers Ida and Tania. Despite coming in last in the last two legs, both have proven to be non-elimination rounds. However, this could be their last chance as they are now faced with a 30 minute penalty if they are not the first team to the pit stop in this leg. In this leg's Roadblock, the chosen team member must perform a bungee jump from the top of the Macau Tower to receive their next clue. The first team to complete the task will receive a helicopter ride from Macau to Hong Kong instead of the TurboJET ferry ride. In this leg's Detour, the choice was between Fish or Fill. In Fish, the team members must carry six large swordfish to a nearby restaurant before receiving their next clue. In Fill, teams must fill an intricate floor pattern using colored rice before receiving their next clue.

This is the penultimate stretch – with four teams remaining, one has to go home as only three teams will take part in the final race towards being champions on The Amazing Race Asia. In this leg's roadblock, one team member had to find the correct pheta from 50 men who were walking around the castle. If that person found the pheta with the word "Correct" inside, they received the next clue. In this leg's detour, teams had to choose between Push and Crush. In Push, teams had to go to Datta Shinde Pottery Shop and push the cart with 75 pots one kilometer to Rajkumar Provision Stores in Mahatma Phule Market with 70 or more pots unbroken at the destination before receiving the next clue. In Crush teams had to go to the market, make 40 glasses of sugar cane juice and sell them to earn INR200 or more to receive the next clue.

Four teams remain in India and luckily for Singaporeans A.D. and Fuzzie, the previous leg was a non elimination round. This means there is still a chance to be in the final three teams in the last leg of The Amazing Race Asia. However, team Singapore must come in first in this leg, or face a 30 minute penalty. In this leg's Detour, teams had to choose between Carpet and Count It. In Carpet, team had to walk to the carpet shop and find two exact carpets, using the images in the Sony Cybershot as references. In Count It team had to walk to a shop and count the dry lime and will only receive their clue once they state the correct amount to the shop owner (correct numbers were 1601, 1595, 1598 and 1577). This leg's Roadblock, one team member must zip across the canyon to the other side to receive the next clue.

After 10 weeks of washing buses and elephants, numerous vehicular problems, dealings with chickens and fish, getting tattoos, taxi drivers who did not know the way, Yields and U-turns executed by one team… it has boiled down to the three teams, of which one who will be crowned champion. In this leg's Roadblock, one team member must locate one of seven special keys out of seventy keys buried in the sand using the metal detector to unlock the clue box. In this leg's Detour, teams have to choose between Pull or Plunge. In Pull, teams must kayak to a nearby oyster farm and find the marked shell by pulling the oyster lines, then the teams must bring the marked shell back to the beach to exchange it with their next clue. In Plunge, teams must snorkel and search for a giant clam shell with a pearl inside; the pearl should be exchanged with their next clue.