Snake-catchers Simon Keys and Siouxsie Gillett face a deadly forest cobra that is hiding out in a tree. The forest cobra is an excellent climber, and its bite could lead to muscle paralysis in minutes — not something you want to experience ever, let alone 15 feet up a tree! But it’s all in a day’s work for this brave couple. They then respond to a call about a black mamba that has made its way into a man’s home. Black mambas tend to get aggressive when cornered. Their venom affects both the heart and the nervous system, swiftly leading to death if you don’t get to the hospital right away. But the risk is worth the reward for Simon and Siouxsie. They put their lives on the line every day in their obsession to save snakes.

Simon and Siouxsie are woken up in the early hours of the morning with a call from panicked residents: a very large snake is slithering around their village, eating their livestock. There is only one snake that is capable of taking on large mammals in this area — the southern African python. A big snake like that, capable of killing a small child, is considered to be a huge threat to a community. Simon is concerned that the frightened members of the community will take matters in their own hands and either attempt to catch the snake or, worse, kill it. Time is of the essence, and the snake-catchers know they need to prepare themselves for either outcome. On another call out, Simon and Siouxsie find themselves working to the clock of nature itself. Instead of running into a situation and removing a snake as quickly and swiftly as possible, this time they have to wait: A hungry forest cobra wants to finish its breakfast first.

Simon and Siouxsie travel from one side of the city to the other, responding to the cries for help as snakes wander into the wrong places. The snakes are everywhere. At one man’s home, a black snake was seen entering a dark room but quickly disappears. The snake could be anywhere, and the situation is far from ideal. They search with torchlight, but something is not right; Simon has a funny feeling that something is going to go very wrong.

It’s midsummer in Durban, South Africa, and for snake-catchers Simon Keys and Siouxsie Gillett, the phone calls are stacking up as people from all walks of life are encountering dangerous and deadly snakes. They receive a call about a giant lizard that snuck into a garden and got into a fight with a dog. By the time Simon and Siouxsie get there, the battle is lost for this monitor lizard, and it has suffered severe injuries. The situation is not good. The two then head off to search for two green snakes that have entered a child’s bedroom. It is unusual to have two snakes traveling together, which raises concern for Simon as this doubles the chance of an encounter with a deadly, venomous snake. One of them could be the deadly Boomslang or even the feared green mamba. If either of those were to bite a child, the consequences could be fatal.

Tattooed snake-catching team Simon Keys and Siouxsie Gillett have had a hectic summer of catching snakes in Durban, South Africa. Today, their first call comes in an hour before sunrise, and it’s their most unusual job yet: snake on a train! Armed with grabsticks and flashlights, Simon and Siouxsie run alongside the train in the dark, jumping over trenches and signaling gear. It could be anything from a harmless house snake to a spitting cobra out hunting at night or even a black mamba that’s been disturbed. It’s a race against time. This train is leaving to pick up 200 passengers at the next station. A venomous snake on the train could spell disaster when the passengers board. Little do they know that the snake they’re looking for has deadly venom, which, drop for drop, is even more potent than that of the black mamba.

Snake-catchers Simon Keys and Siouxsie Gillett are faced with a tricky situation — a woman spotted a large snake slithering around in her garage and is having trouble locating it. From her description, the snake sounds like it could be a black mamba, but Simon and Siouxsie can’t confirm without getting up close and personal with the deadly intruder. If it is a black mamba, the slightest mistake could be fatal, and without access to anti-venom a bite will result in death.