A cursed Gypsy's statue causes Sam and Penny's spirits to take flight and exchange bodies after they made an idle wish about each other having the better life. Now Sam is his wife and Penny is her husband. Oh Boy!

Penny's old boyfriend shows up with a job offer that Penny hopes Sam won't refuse now that he literally speaks for her! Penny is excited to see him, and perhaps a bit too affectionate considering her currently male body! But Sam suspects the former boyfriend is more interested in making a move on Penny! Thanks to the magic statue's body exchange a few weeks ago, he's in the perfect position to find out since her ex-boyfriend believes he IS Penny!

Penny informs Sam that her monthly visitor is overdue to visit HIM! Could Sam become the first man to become a mother??? A way too intense visit to Penny's gynecologist is the next step, with the horror stories of the mothers to be in the waiting room putting birth in a new perspective for him now that HE would be the one giving birth. The Doctor examines him. She asks him if he has been under any stress lately since that could explain the late period. She says that the results of her exam and blood tests will be due in a few days. Penny and Sam have a good laugh when Sams tells her that stress might be a cause for the delay. Changing bodies and genders has certainly been stressful for them both! Sam can only wait for the test results to find out if he is... PREGNANT!

Sam and Penny prepare to participate in a charity touch football game, only Sam is now the cheerleader and Penny is the quarterback and neither has a clue on how to perform those roles!

Penny's family comes to visit on the occasion of her sisters wedding, and masculine minded Sam has to be the daughter/sister instead of Penny, to Sam's annoyance and Penny's disappointment. But when her father threatens to skip the wedding, Penny, still stuck inside Sam's body, has to break through her father's reservations about his son-in-law and show him the error of his actions regarding BOTH his daughter's choices in spouses.

Shhhh. Sam is invited to a fraternity reunion, only the wives are not invited! Too bad Penny is now occupying Sam's body and is the one to get the news! So they both return to Sam's old college for a wild reunion!

The magical statue is STOLEN!!! Will Sam and Penny be cursed to stay in each other's body forever?