Katrina is on the case to help a ""Renegade"" mustang thet needs a little horse whispering and break up catastrophic cat fights between two abyssinians.

Julianne Spraigins is worried how her dog, Elvis, will react when her newborn baby comes home. How can she calm the transition? Katrina helps rescue an abandoned baby squirrel with the help of Mary Cummins, a licensed wildlife rehabilitator with Animal Advocates. Katrina helps coax a shy iguana out into the open.

Sherry has a pet opossum, Unfortunately, Dr.Kat has to break the news that opossums are wild animals, and Sherry is going to have to give away her pet.

Kelly recently lost one of her Border Collie's to old age and her other four dogs become depressed. Katrina advises how to handle their depression. Also, Kat has her hands full with a family, with forty-two pets, that wants to adopt a monkey.

Steve's horse Buzz has lost his buzz in the arena and asks Katrina to help. A family needs help to discover the gender of their pets and seeks advice on a new pet.