Doctor Jane, a famous psychiatrist in Phuket, is woken up by Athin, her husband, who had just returned from abroad. The following day, Jane asks Athin to drop off Patch and Ploy, their children, at school. She borrows Athin's scarf to work. Jane puts that scarf on at her office and notices a strand of blonde hair on it. She is confused and shocked. Her suspicion builds up. She talks to Aunna, her good neighbor, and Doctor Rose, her best friend. They both tell her she's being paranoid. Knowing that Athin has been lying, Jane hires Toey to tail him. Toey tracks Athin down to an apartment building, where she sees him with another woman who shares a farewell kiss with him before he leaves.

Tin notices Jane is still suspicious of him. He reassures her that he doesn't have an affair and kisses her. Doctor Jane, Doctor Rose, and Director Praphat visit Dr. Kirk, Assistant Director of PHC Hospital, who is grieving the loss of his partner. Toey suggests Jane look through Tin's backpack in the trunk of his car. At Tin's birthday party, Jane finds his second phone. The wallpaper of that phone is a photo of himself and another woman, Kate, Lady Mintra and Than Booya's daughter. Jane is shocked. She also finds a group photo of Tin, Kate, Doctor Rose, Aunna, Chach, and June and realizes everyone has betrayed her.

Kate finds out she's pregnant. She wants an abortion, but Doctor Rose advises her to see a psychiatrist. Doctor Jane and Kate come face to face for the first time. Jane confronts Tin and asks if he's cheating on her. Tin responds by getting angry and throwing a fit. Jane knows everything, yet she can only keep the pain inside. Tul, a famous male actor, has a session with Doctor Jane. Good feelings begin to build up in his heart. Kate comes to an abortion clinic with her close friend, Non. Athin finds out from Rose and rushes to stop her. Upon seeing Athin, Kate changes her mind and keeps the baby.

Doctor Jane sees a lawyer in preparation to file for a divorce. Tul and Jane have a chance to meet at a bar. However, someone takes a photo of them and posts it, causing a huge wave of rumors. Patch has an altercation with Mark, a classmate at school after Mark speaks ill of Jane following the rumors. Doctor Jane wants Athin's financial record and contacts Chach, who oversees his accounting. Chach meets Doctor Jane and makes her an offer.

Ploy suffers an asthma attack. Patch tries to reach Athin but fails. Athin is with Kate when he learns that his daughter is sick. He leaves Kate and goes home, leaving Kate to feel like she and her baby are neglected. Lady Mintra plans to introduce Kate to Pita, a young and passionate businessman. Jane's family runs into Kate's family with Pita at a restaurant. Jane notices how Athin is visibly upset with Kate and Pita. Jane then visits Soison, Athin's mother, and tells her she's determined to divorce. A huge argument ensues and alerts the caretakers. Athin and Kate get into a fight. They finally break up.

Soison passes away in the middle of the night with a large bottle of sleeping pills by her side. Jane and Athin come home and tell their children of their grandmother's passing. Soison's death prompts Jane to change her mind about divorcing. Aunna and Chach spot Athin and Kate making out in a car at Soison's funeral. They reconcile. Athin arranges a meeting with a lawyer. Jane is confronted by Dan, who blackmails her. The next day, the hospital's social platform gets filled with accusations against her, causing controversy. The Director summons her for an urgent meeting, where she finds out she is now a suspect in Soison's death.

Doctor Jane becomes a suspect in her mother-in-law's death and gets suspended from work. Apart from that, she also faces accusations on the hospital's social media platform, further increasing negativity. Saifah informs Jane that Doctor Rose is the one who told the police about the sleeping pills that made Jane a suspect. Jane confronts Rose and tells her they were actually Doctor Kirk's sleeping pills. Though free of suspicion, Jane is still dealing with negative comments. Jane finds out that Aunna is the one behind everything.

Kate attends Lady Mintra's birthday party with Pita. She decides to start taking action. Kate provokes Athin and tells him to choose between her and Doctor Jane. Now facing a dead end, Athin becomes stressed. That night, Doctor Jane tells him that Kate once asked her about abortion. Athin is shocked to find out Jane knows, but he has to pretend. Doctor Jane finally sees the painful image of Athin together with Kate. She decides to leave Krabi. Patch and Ploy rush to the rooftop to tell their dad that their mom has gone, only to see the same thing their mom saw.

Doctor Jane goes back to her hometown. She tells Doctor Kirk and Aunt Nat everything. They both tell her to get a divorce. Kate visits Athin at his home. Ploy overhears them and thinks her mother has come home. She goes downstairs only to see Kate instead of her mother. Doctor Jane decides to let everything go and drowns herself in the sea. Tul goes looking for Jane and sees her shoes left on the beach. He jumps into the water, hoping to save her. However, Doctor Jane decides to go home and apologizes to her family for causing trouble. Athin becomes suspicious upon seeing Jane's total turnaround.

Doctor Jane brings Athin to have dinner at Than Booya's house. Everything is going exactly as Jane plans. At that dinner, Jane decides to reveal everything about Athin and Kate to Lady Mintra and Than Boonya. They are both shocked to hear it. Once the chaos calms down, Athin follows Jane outside, where she reveals to him that she slept with Chach. Athin chooses to leave with Kate. Athin blackmails Doctor Jane with the fact she lost control and gathers his evidence against her in court. Jane takes her children away, but they choose their dad over her. Thinking she had hurt their children, Athin loses control and attacks Jane, causing her to bleed.

Two years later, Doctor Jane's life is once again peaceful. Her relationship with Tul is progressing. Patch and Ploy come home to see an envelope with their names. Doctor Jane opens it to find that it's an invitation from Athin and his new family. Athin comes to school to surprise Patch and Ploy. Both kids act awkwardly upon reuniting with their dad since they still remember what happened. Athin sincerely apologizes to his children and asks for another chance. They both start to open up to their dad once again. However, once Ploy meets Lily, Athin and Kate's daughter, she becomes rebellious and upset. Athin provokes Jane, prompting her to rush to the party to take her kids home. Everyone there sees Jane as some weird freak. Jane looks for her children all over the house and ends up in Athin and Kate's bedroom. She explores their bedroom and notices that the content of Kate's bedroom is similar to hers.

Doctor Jane gets angry at Patch for breaking his promise. Patch tries to explain, but Jane grounds him for a week. Patch gets upset. Meanwhile, Ploy feels neglected by her dad, who prioritizes Lily. At school, Ploy starts a strange behavior while Patch gains attention thanks to Athin's fame. Patch and Nana's childhood romance starts building up. While Patch hangs out with Nana, he realizes he forgot Ploy at school. Doctor Jane is fuming and will not listen to any excuse Patch makes. Patch decides to move in with him. Doctor Jane regrets her actions and tries to apologize to Patch, who ignores her plea.

Doctor Jane meets Toey again. Kate and her mother try to defame Doctor Jane's good name. But Doctor Jane manages to pull herself together. Both of Doctor Jane's children start to rebel due to their family problems. Athin hatches a plan to give payback to Chach.

Aunna ends her relationship with Chach. Patch comes home late and upsets Kate. An argument ensues between them. Kate criticizes Doctor Jane harshly and hugely offends Patch. He replies with some harsh words. Having heard what Patch says, Athin slaps him. Tul saves Patch from getting assaulted by a group of teenagers. Doctor Jane is shocked and upset that Patch chooses to see a doctor over talking to her. Jane and Athin reignite their feelings for each other, resulting in an intimate encounter.

Athin finds out about Ploy's stealing tendencies. He criticizes Doctor Jane heavily for not raising their kids properly. Patch went overboard in his relationship with Nana. Doctor Jane talks to Patch about what had happened, but Patch gets upset at his mom for interfering and tells her she has no right to teach him morals. Kate kicks Patch out of the house, thinking he attacked Lily. Athin asks Patch to stay with his mom for a while. Patch refuses, and Athin pushes him down to the ground. At that moment, Doctor Jane arrives and argues with Kate and Athin. Doctor Jane has a heart-to-heart with her son, Patch, who reveals everything. Jane decides to quit her job and leaves town for the sake of Patch and Ploy.

Kate visits Doctor Jane at a hotel. She is shocked to find her parents there with Doctor Jane. Doctor Jane intends to reveal her affair with Athin, but Kate interrupts her by saying she already knows. Athin reluctantly confesses and explains that everything is part of Jane's scheme, and he just fell for her trick. Jane says Kate is living Jane's younger life. Athin comes home to see a moving service team carrying his stuff outside. Kate decides to end her relationship with Athin, leaving him with nothing. Athin decides to say his final farewell to the kids. Patch gets angry at his Dad for hurting his and his sister's feelings. Jane says her final farewell to Athin.