Trinity Blood
The Crown of Thorns I: City in the Mist (1x23)
:
Cain, having killed his brother, Abel, plots with Kampher to destroy the people of Rome and, soon after, the world.
Sister Esther mourns beside a grave of Abel, when there's an attack on Albion. Virgil tells Esther that she's the Star of Hope, the one who is to lead Albion and the world to peace.