InuYasha

Return of the Tragic Priestess, Kikyo (1x15)

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Now that Urasue has kidnapped Kagome, she prepares for the soul transfer, which Inuyasha unknowingly activates. Once the soul is transferred, Kikyo attacks Inuyasha. Inuyasha learns of his supposed betrayal of Kikyo, 50 years ago. Kagome soon reclaims her soul and Kikyo runs off to retain at least part of it Inuyasha chases after and thinks back to when Kikyo convinced him to use the Shikon no Tama, to become Human!