Blindsided by a cheating scandal, blackmail, and divorce, the Estefans put it on the table for the first time in the series premiere of Red Table Talk: The Estefans.

The Estefans reveal their private and deeply personal struggles with mental health issues and how they cope. Performer and social media star Lele Pons candidly shares her extreme challenges of living with severe OCD, and actress Karla Souza tells how growing up with a bipolar mother led to her own dramatic battle with mental illness.

In April, 20-year-old Army Specialist Vanessa Guillén was found dead outside a Texas Army Base. Now, her devastated family has come to the Red Table demanding justice and seeking answers. Vanessa’s heartbroken mother sits down for an emotional one-on-one conversation with Gloria and reveals why she feels there is more to the story surrounding her beloved daughter’s death. Vanessa’s impassioned sisters share their gut-wrenching journey and the important work they’re doing to ensure this never happens again.

When the Estefans survived a horrific bus crash, doctors feared Gloria would never walk again or have more children. Gloria proved them all wrong and now the Estefan family reveal the inspirational life lessons they learned and the stories they’ve never told about the accident that changed their lives forever.

Estefan family friend and popular international actress Kate Del Castillo comes to the Red Table to reveal what really happened during her secret meeting with one of the world’s most dangerous drug lords, El Chapo Guzmán, and how it led to an intimate relationship with actor Sean Penn that ended in a highly publicized feud. Plus, Kate shares how two failed marriages inspired her to live life on her own terms.

The Estefans share their personal and gut-wrenching journey through grief as they remember the devastating losses of Gloria and Lili's mothers and Emily's Abuela. Gloria's sister also reveals her traumatic miscarriage and the ongoing pain she struggles with daily. Plus, a world-renowned expert on loss joins the table and shares the SIX stages of grief and how to find meaning and healing after losing someone you love.

Join The Estefans for a special conversation with one of the most powerful Latinas in the country, Justice Sonia Sotomayor. From the projects to earning her seat on the highest court in the land, Justice Sotomayor’s incredible life story defies all odds. Now she's bringing her invaluable wisdom and priceless life lessons to the Red Table.

For the first time, Gloria reveals her own traumatic childhood experience with a sexual predator in a powerful conversation with the first Latina Bachelorette, Clare Crawley. Clare shares her story of being molested by a Catholic priest. Dr. Ramirez details the warning signs to identify abuse in children.

Cuban people are being beaten, tortured, and jailed for simply wanting to be free. In this very personal episode, the Estefans share their harrowing stories of escape from their homeland. Plus, Afro-Cuban star, Laz Alonso, reveals the horrors of life in Cuba today and a desperate daughter joins the table to plead for her father's life. Singer Yotuel joins Gloria and Emily for a special performance of Patria y Vida (Homeland and Life), a forbidden anthem of the rebellion that's become the urgent cry of the people.

The Red Table gets heated as the Estefans discuss colorism within the Latin community. 1 in 4 Hispanics identify as Afro-Latino and many face discrimination from both their Black and Latin sides. Queer Eye’s Karamo Brown speaks candidly about how he grappled to accept his Cuban roots as a Black man, while singer and TV star, Amara La Negra, reveals how she experienced racism on the set of a popular television show. Plus, we break down the difference between Race and Ethnicity.

Fierce Latina superstars and real-life friends, Becky G and Anitta join the Estefans for real talk about sex, sexism, and love. Becky G reveals she had a “mid-life crisis” at age 9 and how ignoring the advice of music executives led to one of her biggest hits. Anitta confesses one of her dating challenges and how her mom reacted when she came out as bisexual.

The Estefans reveal their own paranormal experiences as renowned psychic medium Matt Fraser connects a skeptical Lili to her mother who died 43 years ago. A grieving mother shares emotional messages from her 6 year old son after his tragic death, and a survivor of a near death experience describes what happened during the 30 minutes she was trapped underwater and drowned.

How well do you know the men in your life? In a RTTE first, The Estefans invite only men to the Table for a vulnerable and eye-opening conversation. Superstar Mexican boxer, Canelo Alvarez, shares a side of himself most don’t know. Actor and author, Justin Baldoni, has a warning for parents of boys and reveals how he never felt “man enough” growing up. It’s Real Talk where men actually open up about their feelings.

The shocking collapse of the Champlain Towers South in Surfside, Florida, destroyed a tight-knit community in an instant. As neighbors, the Estefans watched in horror as only 35 people were rescued from the rubble. In this powerful episode, the family pays tribute to the lives that were forever changed with stories of grief, survival, and love.

Two wildly different marriages are explored: one open, one monogamous. For the first time, Gloria and Emilio share their epic love story while Younger star Nico Tortorella and their spouse Bethany Meyer reveal how they navigate their polyamorous marriage and break down their relationship from a modern, non-binary, sexually fluid, point of view. It’s an unexpected look at what it means to be married today

Reality star and admitted plastic surgery addict Nicole Zavala, shares her plans for a fourth Brazilian Butt Lift despite her doctors' warnings. Nicole's concerned siblings come the table for an intervention. Youtube mega-star Gabi DeMartino, tells what drove her to 80-plus cosmetic procedures. Plus, Lili reveals why she regretted getting breast implants.